MK-2866 is a selective androgen receptor modulator (SARM) developed by a Memphis pharmaceutical company called GTx INC.
The SARM, which is also known as Enobosarm and GTx-024, is currently being researched for its ability to help prevent muscle loss, muscle wasting, and overall dystrophy.
Anecdotal evidence shows that MK-2866 is one of the safest and most effective anabolic SARMs on the market.
It works similarly to testosterone but without any of the adverse side effects like messing with the natural test production.
Instead, this SARM focuses on increasing natural androgenic activity in bone tissues and muscle.
When taken in conjunction with a strict training regime and a balanced healthy diet, MK-2866 can have similar effects to a cycle of Dianabol or Test-E but without any of the negative side effects.
It doesn’t have any effect on the prostate, the liver or the brain.
That’s what the supplement manufacturers’ claim, but there’s no telling how much of this “evidence” is true. Keep in mind that they’re trying to sell a product so they’re obviously going to market it as an anti-catabolic and anabolic supplement without the adverse side-effects that you’d expect.
The following information is a summary of the available clinical and scientific data on the effectiveness of Ostarine on fighting and/or preventing muscle-wasting.
2.1 Increases Muscle Mass and Boosts Strength
Research is on-going to determine the effects of Ostarine on cancer patients and elderly persons that experience muscle loss and muscular dystrophy.
For instance, a clinical trial with MK-2866 was conducted with a healthy group of 120 elderly individuals who were given 3mg of Ostarine per day for 12 weeks.
At the end of the trial, the individuals experienced improved fitness and more lean muscle mass than before. The group that was given 3mg gained a total of 1.3kg lean body mass (2.8 lbs).
The most notable fact was that they also lost 0.6kg (0,3 lbs) fat mass whilst on Ostarine. So they gained muscle and lost fat.
At the end of the trial, the individuals experienced improved fitness and more lean muscle mass than before. The group that was given 3mg gained a total of 1,3kg lean body mass(2.8 LBS).
It’s important to note here that no steroid-like side-effects or risks were observed, and MK-2866 only works when taken in the mentioned dosage, while lower doses don’t show the same effects.
In another clinical trial, 159 cancer patients were split into two groups, with one given 1mg of MK-2866 and another 3mg of MK-2866 per day for 4 months.
At the end of the trial period, both groups showed increased lean muscle mass without any adverse side effects.
In yet another study, rats that were given MK-2866 orally showed that the body easily assimilates and distributes this SARM. Results also showed that it’s quickly eliminated through detox pathways.
With that said, large-scale studies have yet to be conducted to show the effects on MK-2866 on cancer patients that are experiencing muscle loss.
2.2 Helps with Bone Health
It’s common to experience poor bone health as we age due to the deterioration of bone-protective sex hormones in the body.
This often leads to conditions like osteoporosis and other bone diseases. One way to fight such deterioration is to improve bone mineralization and increase muscle mass.
The latter is even more important because muscle mass plays a huge role in strengthening the skeletal system and improving bone strength.
Ostarine has a whole host of benefits to offer including the prevention of bone diseases and promoting speedy recovery from bone fractures.
However, these claims about MK-2866 are supported only by animal studies and there are no human studies to corroborate them.
2.3 Protects Heart Health
A clinical study involving 120 healthy subjects of advanced age showed that Ostarine can help lower bad HDL cholesterol levels as well as blood fats like triglycerides. These results were based on a daily dosage of 1 to 3mg per day which helped to maintain healthy lipid levels.
This is crucial for the prevention of heart disease, and these results show us that Ostarine may be a good idea for heart disease sufferers who are dealing with muscle wasting.
2.4 Increases Insulin Resistance
Based on the same study mentioned above, Enobosarm can lower blood glucose and increase insulin resistance. These are the same effects that anti-diabetic drugs like metformin show. Additional research is required to prove the benefits of Enobosarm on metabolic syndrome and diabetes but the data is promising.
There is no one size fits all approach when it comes to the usage of MK-2866. Some bodybuilders prefer to use it on its own for purposes of body re-composition, while others like to stack SARMs.
For example, the triple stack is a combination of MK2866, Andarine and Cardarine.
So far, research shows that MK-2866 doesn’t come with any side-effects.
That’s because it doesn’t have an estrogenic nature. No user or study has reported any health issues either like bloating, water retention, liver toxicity, prostate problems, high blood pressure or cardiovascular issues.
However, anecdotal evidence suggests that taking MK-2866 in high dosages for 8 to 12 weeks can lead to lowered testosterone levels. The good news is that this effect is only temporary and testosterone levels should get back to normal 3 to 4 weeks after stopping the intake of the SARM.
If you are interested in learning more about this compound definitely check out the following video.
MK-2866 is a powerful and effective SARM which has the ability to improve strength, endurance, and lean muscle mass while healing several health conditions.
It’s versatile enough for use in the cutting and bulking phases and it has no recorded side effects.
To get the most out of MK-2866, it’s recommended to take it in dosages of 20 mg to 25 mg per day. You can also stack it with other SARMs like GW-501516 to achieve better fat loss and improved muscle mass.