Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Aromatase is an enzyme that works to help produce the hormone estrogen. Some cancers use estrogen to grow. By inhibiting aromatase, these estrogen driven cancer cells may stop growing. Exemestane is an aromatase inactivator, which works to decrease the overall levels of estrogen in a woman's body. In women who have gone through menopause, estrogen is mainly produced by the aromatase enzyme, which converts androgens (sex hormones produced by the adrenal glands) into estrogens. Exemestane binds to aromatase, changing the protein permanently. This change "turns off" aromatase so that it can no longer make estrogen. While estrogen may not actually cause breast cancer, it is necessary for the cancer to grow in certain breast cancers. With estrogen blocked, the cancer cells that feed off estrogen may not be able to survive.
Exemestane comes as a tablet to take by mouth. The tablet should be taken once a day after a meal. Take exemestane at around the same time every day.
Store your medication in the original, labeled container at room temperature and in a dry location (unless otherwise directed by your healthcare provider or pharmacist). This medication should not be stored in a pillbox. Keep containers out of reach of children and pets.
Aromasin has the ability to increase free Testosterone and IGF (Insulin Growth Factor) levels in the body. Because of this, this drug is also very useful during PCT (Post Cycle Therapy) regimes when one is trying to restore natural Testosterone production levels in order to avoid a post cycle “crash”. Since one of the main goals of PCT is getting estro under control, the very last thing you want is a big estro spike right at the end. Aromasin prevents this from occurring, keeping estrogen under control, preventing rebound and getting you on the right track to a full and efficient recovery.
In a study, Aromasin dosed at 25mg per day increased total testoste by 60% in only 10 days. Even better than that, is the fact that free (useable) testoster increased over 100% in the same time frame! In addition, Aromasin also increases IGF-1 levels. There is no estrogen rebound from Aromasin, and it is also a very powerful and effective treatment for gynecomastia. All of this makes Aromasin a no-brainer for post cycle therapy as well as on cycle estrogen control.
The more you take, the greater is suppressed estrogen level and this, as we said above, is bad for your health. However, in short term, you can do it. If you prepare for a competition and want to get a ripped, dry look than you can take Aromasin in higher dosage but for no longer than 48 hours. Within this frame of time, estrogen level is very low and keeping it this another 24 hours can leads to serious health problems, beginning with your joints, immune system, cholesterol level and others.
The best would be to stuck to a dosage of 20-25 mgs per day and only in rare cases go over this limit and reach your goal. The more careful you are with it use, the higher chances to make Aromasin use very beneficial for your body and to keep unwanted side effects far away.